The Federal Trade Commission (FTC) has announced a landmark settlement with one of the nation’s largest pharmacy benefit managers, Express Scripts, aimed at significantly lowering prescription drug costs for American patients.

Hospital associations and safety-net health systems have filed a federal lawsuit seeking to block the Health Resources and Services Administration’s (HRSA) proposed 340B Rebate Model Pilot Program, which is scheduled to launch in January 2026.

A recent Wall Street Journal investigation found that mail-order pharmacies significantly over-dispensed medications to Medicare patients, resulting in an estimated $3 billion in excess drugs between 2021 and 2023.